Gilyos
world of freeze drying
Gilyos applies the most recent, highly innovative process and analytical equipment and instrumentation related to freeze drying in their labspace. We are more than an end-user of equipment. We partner with industry leaders to develop technologies that extend the understanding of freeze drying processes. Innovations are central to progress for us.
Benefit of the accumulated knowledge of more than 25 years day by day experience in the field of freeze drying, both in an academic and industrial environment: short development times, sound product designs and seamless scaleability of development data.
Quality is our philosophy. We are Iso 9001:2015 certified. Scope of the certification:
"Services provided to the pharmaceutical, diagnostic, medical device, and food industry, with special focus on freeze drying science and parenteral drug delivery applications. The services include formulation and process development, optimization, and scale-up of pharmaceutical, biopharmaceutical, small molecule and food products, analytical and material testing, consulting, and training."
Real conditions in the lab: we have the permission to work with biological agents up to and including Biological Safety Level (Bsl) 2, including human and animal pathogens, and Gmos (Genetically Modified Organisms).
Examples of frequently requested development & consulting services:
- Formulation development of small molecules, proteins, peptides, vaccines, nanoparticles, polyplexes and other complex (drug delivery) systems.
- Thermal characterization of developed formulations (Mdsc, Lt-Fdm, and other techniques).
- Selection of optimum primary packaging material (vial, syringe, etc.).
- Mechanical characterization of packaging materials (stoppers, medical devices, blisters, etc).
- Freeze drying cycle design and and optimization using state of the art Process Analytical Technology (Pat), controlled nucleation strategies and QbD concepts.
- Physicochemical characterization of freeze dried products (e. g. Xrpd, Kf, Dvs, Bet, Sem, and many more).
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Stability testing at Ich conditions.
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Troubleshooting existing cycles.
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Cmo identification.
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Scale-up, scale-down and technical transfer of freeze drying cycles.
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Support in selection (specification) of your new freeze drying equipment (lab to production range).
For more information, please visit our webiste:
LYOSCOPEDIA®
Freeze drying is a multi-disciplinary field which starts with aspects of chemistry and biochemistry during formulation development and ends with engineering principles during manufacturing. A sound understanding of basic principles and fundamentals of the related disciplines is therefore mandatory to successfully accomplish a freeze drying project.
Gilyos has established its own seminar and training program to share our expertise with you:
Lyo(philization)
Scop(e)
(Encyclop)edia
= Lyoscopedia®
Our courses are not standardized, but typically a mixture of an academic lecture and a hands on training. We cover all levels of expertise, i.e. from beginner courses to focussed expert seminars.
For upcoming (public) seminar announcements, please visit our training website:
Note that we also offer custom seminars for our customers.